Table 2.
Anatomical and peri-interventional factors associated with in-hospital outcome
| MC (n=179) | MVrepair (n=185) | I° MVR (n=36) | |||||||
| Success (n=152) | Failed/Died (n=27) |
P value | Success (n=166) |
Failed/Died (n=19) |
P value | Success (n=33) |
Died (n=3) |
P value | |
| Mitral valve anatomy | |||||||||
| Calcification leaflet, n (%) | 6 (3.9) | 3 (11.1) | 0.118 | 5 (3.0) | 3 (15.8) | 0.009 | 17 (51.5) | 1 (33.3) | 0.560 |
| Calcification annulus, n (%) | 41 (27.0) | 9 (33.3) | 0.500 | 20 (12.0) | 10 (52.6) | <0.001 | 14 (42.4) | 1 (33.3) | 0.807 |
| MV prolapse characteristics | |||||||||
| Single segment, n (%) | 37 (24.3) | 3 (11.1) | 0.130 | 55 (33.1) | 5 (26.3) | 0.550 | 3 (9.1) | 1 (33.3) | 0.212 |
| Two segments ant. or post., n (%) | 6 (3.9) | 3 (11.1) | 0.118 | 19 (11.4) | 2 (10.5) | 0.905 | 3 (9.1) | 1 (33.3) | 0.212 |
| Advanced only post., n (%) | 11 (7.2) | 2 (7.4) | 0.975 | 15 (9.0) | 2 (10.5) | 0.832 | 3 (9.1) | 0 (0.0) | 0.598 |
| Advanced ant.+post., not Barlow, n (%) | 17 (11.2) | 3 (11.1) | 0.991 | 40 (24.1) | 4 (21.1) | 0.769 | 5 (15.2) | 0 (0.0) | 0.482 |
| Barlow, n (%) | 5 (3.3) | 0 (0.0) | 0.342 | 21 (12.7) | 1 (5.3) | 0.349 | 5 (15.2) | 0 (0.0) | 0.482 |
| Flail leaflet, n (%) | 53 (34.9) | 4 (14.8) | 0.039 | 80 (48.2) | 11 (57.9) | 0.426 | 8 (24.2) | 0 (0.0) | 0.348 |
| Extent of intervention | |||||||||
| Isolated mitral valve intervention, n (%) | 112 (73.7) | 18 (66.7) | 0.454 | 129 (77.7) | 9 (47.4) | 0.004 | 21 (63.6) | 0 (0.0) | 0.033 |
| MV+PCI (staged) or bypass surgery, n (%) | 27 (17.8) | 9 (33.3) | 0.063 | 14 (8.4) | 3 (15.8) | 0.296 | 3 (9.1) | 1 (33.3) | 0.212 |
| MV+TAVR (staged) or SAVR, n (%) | 15 (9.9) | 1 (3.7) | 0.304 | 6 (3.6) | 4 (21.1) | <0.001 | 3 (9.1) | 2 (66.6) | 0.005 |
| MV+TV intervention, n (%) | 1 (0.7) | 0 (0.0) | 0.675 | 21 (12.7) | 4 (21.1) | 0.313 | 7 (21.2) | 1 (33.3) | 0.640 |
| Triple valve surgery, n (%) | – | – | – | 2 (1.2) | 1 (5.3) | 0.187 | 1 (3.0) | 0 (0.0) | 0.768 |
| Single clip intervention, n (%) | 37 (24.3) | 5 (18.5) | 0.513 | – | – | – | – | – | – |
| Two clips, n (%) | 98 (64.5) | 13 (48.1) | 0.108 | – | – | – | – | – | – |
| ≥3 clips, n (%) | 17 (11.2) | 9 (33.3) | 0.002 | – | – | – | – | – | – |
ant., anterior; MC, Mitraclip; MV, mitral valve; MVR, surgical MV replacement; MVrepair, surgical mitral valve repair; NTproBNP, N-terminated pro-brain natriuretic peptide; PCI, percutaneous coronary intervention; post., posterior; SAVR, surgical aortic valve replacement; TAVR, transcatheter aortic valve replacement; TV, tricuspid valve.