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. 2020 Jul 19;10(7):e035842. doi: 10.1136/bmjopen-2019-035842

Table 4.

Population projections and comparison of medicine costs (US$) for implementing total risk approach versus single risk factor approach in Bangladesh

Estimated annual total cost of CVD medication treatment per million population†
Total risk approach CV risk ≥20% alone
Total no of people in the general population (in thousands)* Percentage of population aged ≥40 years requiring medication (%) Total no of people estimated to require drug treatment (in thousands) No of people per million population (aged 40 years and older) Aspirin (US$) Enalapril (US$) Hydrochlorothiazide (US$) Simvastatin (US$) Total (US$)
Age group
Men
 40–49 9210 0.4 3660 4000 6570.0 34 748.0 12 118.0 62 196.0 115 632.0
 50–59 6303 0.1 596 1000 1642.5 8687.0 3029.5 15 549.0 28 908.0
 60–69 3730 1.5 4733 15 000 24 637.5 130 305.0 45 442.5 233 235.0 433 620.0
 ≥70 1881 7.0 17 507 70 000 114 975.0 608 090.0 212 065.0 1 088 430.0 2 023 560.0
 Total 21 124 1.0 20 769 10 000 16 425.0 86 870.0 30 295.0 155 490.0 289 080.0
Women
 40–49 9087 0.0 0 0 0.0 0.0 0.0 0.0 0.0
 50–59 5662 0.0 0 0 0.0 0.0 0.0 0.0 0.0
 60–69 3257 0.0 0 0 0.0 0.0 0.0 0.0 0.0
 ≥70 1638 1.6 3965 16 000 26 280.0 138 992.0 48 472.0 248 784.0 462 528.0
 Total 19 644 0.1 1958 1000 1642.5 8687.0 3029.5 15 549.0 28 908.0
All
 40–49 18 296 0.2 3605 2000 3285.0 17 374.0 6059.0 31 098.0 57 816.0
 50–59 11 965 0.1 1134 1000 1642.5 8687.0 3029.5 15 549.0 28 908.0
 60–69 6989 0.7 4206 7000 11 497.5 60 809.0 21 206.5 108 843.0 202 356.0
 ≥70 3518 4.3 21 410 43 000 70 627.5 373 541.0 130 268.5 668 607.0 1 243 044.0
 Total 40 768 0.5 20 175 5000 8212.5 43 435.0 15 147.5 77 745.0 144 540.0
Single risk factor approach: BP ≥140/90 (SBP ≥140 + isolated raised DBP), %
Age group
Men
 40–49 9210 17.1 156 482 171 000 280 867.5 1 485 477.0 518 044.5 2 658 879.0 4 943 268.0
 50–59 6303 21.7 129 375 217 000 356 422.5 1 885 079.0 657 401.5 3 374 133.0 6 273 036.0
 60–69 3730 30.5 96 228 305 000 500 962.5 2 649 535.0 923 997.5 4 742 445.0 8 816 940.0
 ≥70 1881 29.4 73 529 294 000 482 895.0 2 553 978.0 890 673.0 4 571 406.0 8 498 952.0
 Total 21 124 22.1 458 995 221 000 362 992.5 1 919 827.0 669 519.5 3 436 329.0 6 388 668.0
Women
 40–49 9087 22.5 199 643 225 000 369 562.5 1 954 575.0 681 637.5 3 498 525.0 6 504 300.0
 50–59 5662 30.6 164 475 306 000 502 605.0 2 658 222.0 927 027.0 4 757 994.0 8 845 848.0
 60–69 3257 28.7 81 881 287 000 471 397.5 2 493 169.0 869 466.5 4 462 563.0 8 296 596.0
 ≥70 1638 33.7 83 509 337 000 553 522.5 2 927 519.0 1 020 941.5 5 240 013.0 9 741 996.0
 Total 19 644 26.7 522 759 267 000 438 547.5 2 319 429.0 808 876.5 4 151 583.0 7 718 436.0
All
 40–49 18 296 20.2 364 085 202 000 331 785.0 1 754 774.0 611 959.0 3 140 898.0 5 839 416.0
 50–59 11 965 26.3 298 189 263 000 431 977.5 2 284 681.0 796 758.5 4 089 387.0 7 602 804.0
 60–69 6989 29.5 177 236 295 000 484 537.5 2 562 665.0 893 702.5 4 586 955.0 8 527 860.0
 ≥70 3518 31.6 157 336 316 000 519 030.0 2 745 092.0 957 322.0 4 913 484.0 9 134 928.0
 Total 40 768 24.6 992 585 246 000 404 055.0 2 137 002.0 745 257.0 3 825 054.0 7 111 368.0

*Source: Population Projections (using 2011 Census data) Bangladesh Bureau of Statistics, Statistics and Informatics Division, Ministry of Planning

†Price for 100 tablets in US$: Aspirin (0.45), Enalapril (2.38), Hydrochlorothiazide (0.83), Simvastatine (4.29); one tablet taken per da

BP, blood pressure; CV, cardiovascular; CVD, cardiovascular disease; DBP, diastolic blood pressure; SBP, systolic blood pressure.