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. Author manuscript; available in PMC: 2020 Jul 20.
Published in final edited form as: Arch Toxicol. 2019 Dec 10;94(2):469–484. doi: 10.1007/s00204-019-02636-x

Fig. 2.

Fig. 2

Heatmap of three potency-driven activity patterns in k-means clusters of chemical-parameter hits. Blue = increased activity, purple = decreased activity. Darker colors = lower chemical AC50s. Sample dose-response curves shown for an active and inactive chemical-parameter. Red lines = log10(AC50), grey box = 3*BMAD