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. Author manuscript; available in PMC: 2020 Jul 20.
Published in final edited form as: Arch Toxicol. 2019 Dec 10;94(2):469–484. doi: 10.1007/s00204-019-02636-x

Table 1.

Top 15 parameters

Category Parameter Description/definition

General activity (“Firing”) Mean firing rate (Hz) Total number of spikes over the duration of the analysis
Number of spikes Total number of spikes over the duration of the analysis
Number of bursts Total number of single-electrode bursts over the duration of the analysis
Burst structure Burst duration (average) Average time from the first to the last spike in a burst
Interburst interval (average) Average time between the start of bursts
Burst percentage-avg The number of spikes in a burst divided by the total number of bursts, times 100
Burst percentage-std Standard deviation of the burst percentage
Number of spikes/burst (avg) Average number of spikes in a burst
Connectivity Network burst percentage The number of spikes in network bursts divided by the total number of spikes, times 100
#Spikes/network burst-avg The average number of spikes in a network burst
#Spikes/network burst-std The standard deviation of the number of spikes in a network burst
#Electrodes participating in Burst-avg The average number of electrodes participating in a network burst
Area under cross-correlation Area under the well-wide pooled inter-electrode cross-correlation
Full-width at half-height of cross-correlation Distance along the x-axis from the left half height to the center half height of the normalized cross correlogram
Synchrony Index A unit measure of synchrony between 0 and 1

Definitions are summarized from Axion Biosystems neural metric tool metric definitions (v2.4)