TABLE 6.

Cox Proportional Hazard Model for Ependymomas

		Hazard ratio	95% CI	P value
Gender	Female	Reference group
	Male	1.17	1.034 to 1.379	0.043
Age (y)
	0–2	Reference group
	3–9	0.439	0.332 to 0.582	<0.001
	10–19	0.317	0.226 to 0.445	<0.001
	20–29	0.384	0.276 to 0.534	0.001
	30–39	0.357	0.259 to 0.493	<0.001
	40–49	0.479	0.352 to 0.652	<0.001
	50–59	0.839	0.636 to 1.108	0.216
	60–69	1.384	1.029 to 1.861	0.031
	70–79	1.992	1.435 to 2.765	<0.001
	80+	2.949	1.724 to 5.042	<0.001
Site
Spinal cord		Reference group
Supratentorial		3.575	2.881 to 4.435	<0.001
	Cortex	3.517	2.795 to 4.425	<0.001
	Ventricle	3.24	2.507 to 4.188	<0.001
Infratentorial		3.143	2.490 to 3.967	<0.001
	Brain stem	3.081	2.410 to 3.938	<0.001
	Cerebellum	3.214	2.335 to 4.423	<0.001
Other		2.911	0.717 to 11.829	0.135
WHO grade
	Grade II ependymomas	Reference group
	Grade III anaplastic ependymomas	1.639	1.325 to 2.028	<0.001
Surgery
	Yes	Reference group
	No	1.992	1.441 to 2.754	<0.001
*Radiation
	Yes	Reference group
	No	1.748	1.078 to 2.834	0.024

^*Subset of patients (n = 316) who had partial resection.