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. Author manuscript; available in PMC: 2020 Sep 16.
Published in final edited form as: Cancer Cell. 2019 Sep 16;36(3):288–301.e14. doi: 10.1016/j.ccell.2019.08.002

Table 1.

Fraction of Hotspots in Confident False-Positive Genes (Empirical FDR) at the Indicated q Value Cutoff

Method q ≤ 0.1 q ≤ 0.01 q ≤ 0.001
Uniform-within-gene 0.06 (102/1,678) 0.05 (45/920) 0.03 (19/590)
Uniform Poisson 0.05 (82/1,547) 0.03 (29/1,006) 0.02 (14/713)
Gamma-Poisson 0.01 (8/710) 0.01 (5/504) 0.01 (3/387)
Log-normal-
Poisson		 0.0 (0/511) 0.0 (0/290) 0.0 (0/191)