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. Author manuscript; available in PMC: 2020 Jul 20.
Published in final edited form as: Cell Rep. 2020 Jun 30;31(13):107828. doi: 10.1016/j.celrep.2020.107828

Figure 2. SphK1ΔEC Mice Had Fewer AT1 Cells Than WT after PA.

Figure 2.

(A–D) Lung sections from uninjured or 33 PA injured WT and SphK1ΔEC mice were stained for Sp-C and HopX. Without injury (A and B), the numbers of HopX+ cells (arrow) were similar between WT (A) and SphK1ΔEC (B) lungs. After 3x PA injury (C and D), more HopX+ AT1 were present in WT (C) than SphK1ΔEC (D) lungs. Scale bar, 100 μm.

(E) The numbers of HopX+ and Sp-C+ cells were counted and normalized by area, and the ratios of HopX+ to Sp-C+ cells were calculated.

Mean ± SEM. *p < 0.05; **p < 0.01. n.s., not significant. See also Figures S2 and S3.