Table 1.
Association between pathogens included on TaqMan Array cards and intussusception among children <2 years old in 4 Asian countries.
| Cases | Controls | |||||
|---|---|---|---|---|---|---|
| N=249 | % | N=249 | % | OR1 | 95%CI | |
| Adenovirus pan | 119 | 48 | 76 | 31 | 2.67 | 1.75- 4.36 |
| <20 Cq-value2 | 29 | 12 | 7 | 3 | 22.65 | 4.79- 106.96 |
| 20-24 Cq-value2 | 31 | 13 | 6 | 2 | 10.87 | 3.67- 32.26 |
| 25-29 Cq-value2 | 23 | 9 | 16 | 6 | 2.89 | 1.31- 6.41 |
| 30-34 Cq-value2 | 36 | 15 | 47 | 19 | 1.25 | 0.71-2.22 |
| Type C | 93 | 39 | 83 | 35 | 1.24 | 0.82- 1.86 |
| <20 Cq-value2 | 20 | 8 | 3 | 1 | 16.60 | 2.20- 125.50 |
| 20-24 Cq-value2 | 10 | 4 | 2 | 1 | 8.60 | 1.08- 68.16 |
| 25-29 Cq-value2 | 13 | 5 | 21 | 9 | 0.71 | 0.30- 1.66 |
| 30-34 Cq-value2 | 50 | 21 | 57 | 24 | 0.93 | 0.56- 1.53 |
| Non-Type C | 43 | 18 | 25 | 10 | 1.90 | 1.11- 3.27 |
| Type F3 | 7 | 7 | 4 | 4 | 2.00 | 0.50- 8.00 |
| Ancylostoma | 0 | 0 | 0 | 0 | - | - |
| Ascaris | 1 | 0 | 0 | 0 | - | - |
| Astrovirus | 11 | 4 | 16 | 7 | 0.69 | 0.30- 1.62 |
| C. difficile | 36 | 15 | 42 | 17 | 0.90 | 0.54- 1.51 |
| Campylobacter pan | 18 | 7 | 27 | 11 | 0.64 | 0.34- 1.24 |
| C. jejuni/C. coli | 8 | 3 | 20 | 8 | 0.39 | 0.16- 0.93 |
| Cytomegalovirus | 41 | 17 | 42 | 17 | 1.00 | 0.62- 1.62 |
| Cryptosporidium | 11 | 4 | 10 | 4 | 1.14 | 0.41- 3.15 |
| Enteroaggregative E. coli (EAEC) | 101 | 41 | 94 | 38 | 1.20 | 0.79- 1.81 |
| Enteroinvasive E. coli (EIEC) | 8 | 3 | 5 | 2 | 1.60 | 0.52- 4.89 |
| Atypical enteropathogenic E. coli (aEPEC) | 37 | 15 | 38 | 15 | 1.10 | 0.67- 1.82 |
| Typical enteropathogenic E. coli (tEPEC) | 11 | 5 | 22 | 9 | 0.52 | 0.25- 1.09 |
| Enterotoxigenic E. coli (ETEC) | 29 | 12 | 24 | 10 | 1.29 | 0.69- 2.44 |
| E. coli O157 | 4 | 2 | 1 | 0 | 4.00 | 0.45- 35.79 |
| Shiga-toxin producing E. coli (STEC) | 3 | 1 | 2 | 1 | 1.50 | 0.25- 8.98 |
| E. histolytica | 0 | 0 | 0 | 0 | - | - |
| Epstien Barr virus | 2 | 1 | 2 | 1 | 1.00 | 0.14- 7.10 |
| Enterovirus | 86 | 35 | 85 | 35 | 1.00 | 0.67- 1.49 |
| Giardia | 8 | 3 | 12 | 5 | 0.64 | 0.25- 1.64 |
| H. pylori | 1 | 0 | 1 | 0 | 1.00 | 0.06- 15.00 |
| Human herpesvirus 6 | 14 | 6 | 4 | 2 | 3.50 | 1.15- 10.63 |
| Human herpesvirus 7 | 1 | 0 | 0 | 0 | - | - |
| Necator | 0 | 0 | 0 | 0 | - | - |
| Norovirus group I | 5 | 2 | 8 | 3 | 0.63 | 0.20- 1.91 |
| Norovirus group II | 19 | 8 | 36 | 15 | 0.50 | 0.28- 0.90 |
| Rotarix specific NSP2 | 1 | 0 | 0 | 0 | - | - |
| RotaTeq specific VP63 | 0 | 0 | 0 | 0 | - | - |
| RotaVac specific G93 | 0 | 0 | 0 | 0 | - | - |
| Rotavirus | 18 | 7 | 17 | 7 | 1.07 | 0.52- 2.22 |
| <20 Cq-value2 | 3 | 1 | 0 | 0 | - | - |
| 20-24 Cq-value2 | 4 | 2 | 8 | 3 | 0.47 | 0.14- 1.61 |
| 25-29 Cq-value2 | 5 | 2 | 2 | 1 | 2.50 | 0.49- 12.89 |
| 30-34 Cq-value2 | 6 | 2 | 7 | 3 | 0.73 | 0.22- 2.46 |
| Salmonella | 4 | 2 | 9 | 4 | 0.44 | 0.14- 1.44 |
| Sapovirus | 16 | 6 | 24 | 10 | 0.62 | 0.31- 1.24 |
| Strongyloides | 0 | 0 | 0 | 0 | - | - |
| Trichuris | 1 | 0 | 0 | 0 | - | - |
| Y. enterocolitica | 8 | 3 | 2 | 1 | 4.00 | 0.85- 18.84 |
1
Odds ratio
2
Quantification cycle
3
Only 1 version of the card therefore 191/498 samples were tested