Table 1.
Baseline Characteristics.
Variable | B2M >2.5 μg/ml (N=222) | B2M ≤ 2.5 μg/ml (N=288) |
---|---|---|
Age (years), median (IQR)* | 61 (54–66) | 57 (51.4–63.4) |
Male, n (%) | 118 (53%) | 164 (57%) |
Mayo 2012 stage (III/IV), n (%)* | 60/183** (33%) | 17/204** (8%) |
Organs involved >2, n (%)* | 56 (25%) | 41 (14%) |
Cardiac involvement, n (%)* | 113 (51%) | 111(39%) |
NT-proBNP (pg/ml), median (IQR)*# | 692.5 (228–2641) | 194.5 (85–877) |
Troponin (μg/L), median (IQR)*# | 0.01 (0.01–0.03) | 0.01 (0.01–0.01) |
dFLC (mg/dl), median (IQR)* | 22 (8.8–52) | 9 (4–30) |
Kidney involvement, n (%) | 133 (60%) | 161 (56%) |
Liver involved, n (%) | 26 (12%) | 29 (10%) |
FISH: t(11;14), n (%) | 56/164** (34%) | 71/191** (37%) |
BMPC ≥ 10%, n (%)* | 125 (56%) | 114 (40%) |
Difference was statistically significant.
Data was not available in all patients. Percentage is from all patients where the test could be done.
Normal range for NT-proBNP (5–50 pg/ml), normal range for Troponin (≤15 μg/L)
Abbreviations: B2M: beta-2 microglobulin, IQR: interquartile range, NT-ProBNP: N-terminal pro brain natriuretic peptide, dFLC: difference in free light chain FISH: Fluorescence in situ hybridization, BMPC: bone marrow plasma cells.