Table 8.
Subgroup multivariable GEE analyses on the effects of surgical treatment compared with definitive radio-ablation on outcomes in stage I patients (N = 29). Functional EC (primary outcome, 6MWD)
| Variable | β (95% CI) | p value |
|---|---|---|
| Sex (F/M) | 176.4 (134.1, 218.7) | < 0.001 |
| HFrEF (N/Y) | 150.2 (92.6, 207.8) | < 0.001 |
| FEV1% predicted | 2.97 (1.47, 4.46) | < 0.001 |
| Surgical treatment (Y/N) | − 41.0 (− 111.9, 29.8) | 0.27 |
| Time effect (post-/pre-treatment) | − 32.3 (− 67.0, 2.46) | 0.07 |
| Surgical treatment × time effect | 9.91 (− 56.2, 76.0) | 0.77 |
6MWD, six-minute walk distance; β, regression coefficient; CI, confidence interval; EC, exercise capacity; F, female; FEV1, forced expiratory volume in 1 s; GEE, generalized estimating equations; M, male