Table 9.
Subgroup multivariable GEE analyses on the effects of surgical treatment compared with definitive radio-ablation on outcomes in stage I patients (N = 29). Dyspnea (exploratory outcome, UCSD SOBQ)
| Variable | β (95% CI) | p value |
|---|---|---|
| Anxiety/depression/PTSD (N/Y) | − 25.3 (− 36.6, − 14.1) | < 0.001 |
| FEV1% predicted | − 0.24 (− 0.52, 0.04) | 0.09 |
| Surgical treatment (Y/N) | − 11.8 (− 25.6, 2.04) | 0.095 |
| Time effect (post-/pre-treatment) | + 16.8 (+ 9.25, + 24.3) | < 0.001 |
| Surgical treatment × time effect | 2.37 (− 13.2, 17.9) | 0.77 |
β, regression coefficient; CI, confidence interval; FEV1, forced expiratory volume in 1 s; GEE, generalized estimating equations; PTSD, post-traumatic stress disorder; UCSD SOBQ, University of California San Diego Shortness of Breath Questionnaire