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. 2020 Jul 14;12:5759–5771. doi: 10.2147/CMAR.S245283

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© 2020 Qiu et al.

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Effects of MnSOD silencing and overexpression on migration, invasion and EMT. Ad-GFP and Ad-shMnSOD were transduced into HCSLCs, respectively. MnSOD and FoxM1 protein levels (A), cell migratory and invasive capacities (B and C), and E-cadherin, N-cadherin, Twist1 and MMP-2 protein amounts (D and E) in untreated-HCSLCs (Mock), harboring Ad-GFP or Ad-shMnSOD (n=3; *P<0.05 vs Mock; ^#P<0.05 vs Ad-GFP; one-way ANOVA) are shown. MHCC97H cells were transduced with Ad-GFP or Ad-MnSOD. MnSOD and FoxM1 protein levels (F), cell migratory and invasive capacities (G and H), and E-cadherin, N-cadherin, Twist1 and MMP-2 protein amounts (I and J) in MHCC97H cells transfected with Ad-GFP or Ad-MnSOD (n=3; *P<0.05 vs Mock; ^#P<0.05 vs Ad-GFP; one-way ANOVA) are shown.