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. 2020 Jul 15;14:2775–2787. doi: 10.2147/DDDT.S253280

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© 2020 Wang et al.

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Schematic diagram of tanshinone IIA promoting axonal regeneration and neuroprotective effect on focal cerebral ischemia in rats by inhibiting the Nogo-A/NgR1/RhoA/ROCKII/MLC signaling pathway.

Abbreviations: Nogo-A, neurite outgrowth inhibitor-A; NgR1, Nogo receptor 1; RhoA, Recombinant Ras Homolog Gene Family, Member A; ROCKII, Rho-associated protein kinase 2; MLC, myosin light chain.