Table 5. Results of Univariate and Multivariate Analysis of MRI Features for Overall Survival and Disease-Free Survival.

MR Features	Values	Univariate Analysis			Multivariate Analysis
		HR	95% CI	P	HR	95% CI	P
Overall survival
Post-CRT MRI
ycN category		2.295	1.281–4.114	0.005
Negative	240
Positive	81
EMVIpost		3.314	1.547–7.101	0.002	2.259	1.006–3.218	0.048
Negative	294
Positive	27
EMDpost		1.082	1.015–1.153	0.016
Mean	2.38
SD	3.39
mrTRG
5-point grading		6.615	1.188–31.993	0.024
Binomial classification		2.172	1.205–3.913	0.010
Disease-free survival
Pre-CRT MRI
EMVIpre		3.120	1.605–6.068	0.001
Negative	279
Positive	42
Post-CRT MRI
ycT category*		2.148	1.161–3.973	0.015
Good*	166
Poor	155
ycN category		2.501	1.369–4.569	0.003
Negative	240
Positive	81
Extramesorectal LNpost		3.273	1.650–6.491	0.001	2.610	1.290–5.281	0.008
Negative	285
Positive	36
EMVIpost		5.879	2.947–11.727	< 0.001	5.011	2.463–10.195	< 0.001
Negative	422
Positive	50
EMDpost		1.111	1.045–1.181	0.001
Mean	2.772
SD	3.826
mrTRG
5-point grading		7.974	1.445–44.015	0.039
Binomial classification		1.917	1.044–3.522	0.036

^*Tumors are graded into two groups (good and poor responders) according to ypT category. ypT1, T2, T3a are classified as good responders and ypT3b, T3c, T3d, and T4 as poor responders. CI = confidence interval, HR = hazard ratio