Table 3. Diagnostic Performance of Combined Use of Quantitative Parameters of SWE and SMI with B-Mode US in Differentiating Malignant from Benign Masses.
Variables | AUC | 95% CI | P§ |
---|---|---|---|
B-mode US alone | 0.719 | 0.649–0.789 | NA |
Set 1* (selective downgrade of category 4a) | |||
B-mode + Emax | 0.829 | 0.769–0.890 | < 0.001 |
B-mode + Eratio | 0.772 | 0.705–0.838 | 0.092 |
B-mode + SMIVI | 0.778 | 0.713–0.843 | 0.047 |
Set 2† (reassessment of both category 3 & 4a) | |||
B-mode + Emax | 0.742 | 0.671–0.813 | 0.894 |
B-mode + Eratio | 0.685 | 0.611–0.760 | 0.167 |
B-mode + SMIVI | 0.687 | 0.613–0.761 | 0.424 |
Set 1 and Set 2‡ | |||
B-mode + Emax + Eratio + SMIVI | 0.849 | 0.792–0.905 | < 0.001 |
*Selective downgrade for only BI-RADS category 4a lesion when each value was lower than respective cutoff value, †Reassessment of BI-RADS category for both category 3 and 4a. Selective downgrade for category 4a when each value was lower than respective cutoff values and selective upgrade for category 3 when quantitative values higher than respective values, ‡Selective downgrade if one or no parameter for exceeding cutoff values, selective upgrade if all three parameters for exceeding cutoff values, §p values indicate comparison of diagnostic performance of between BI-RADS alone and addition of quantitative parameters. US = ultrasound