Table 4. Effect of Downgrading BI-RADS Category 4a Lesions with Combined Use of Quantitative Parameters of SWE and SMI in Addition to B-Mode US (Set 1).
| Variables | Sensitivity (%) | P† | Specificity (%) | P† | Accuracy (%) | P† | PPV (%) | P† | NPV (%) | P† | AUC | P† |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B-mode* alone | 97.6 (83/85) | NA | 46.1 (53/115) | NA | 68.0 (136/200) | NA | 57.2 (83/145) | NA | 96.4 (53/55) | NA | 0.719 | NA |
| B-mode + Emax | 85.9 (73/85) | 0.037 | 80.0 (92/115) | < 0.001 | 82.5 (165/200) | 0.001 | 76.0 (73/96) | < 0.001 | 88.5 (92/104) | < 0.001 | 0.829 | < 0.001 |
| B-mode + SMIVI | 92.9 (79/85) | 1.000 | 62.6 (72/115) | 0.069 | 75.5 (151/200) | 0.567 | 64.8 (79/122) | 0.027 | 92.3 (72/78) | 0.497 | 0.778 | 0.047 |
| B-mode + Emax + Eratio + SMIVI | 90.6 (77/85) | 0.199 | 79.1 (91/115) | < 0.001 | 84.0 (168/200) | < 0.001 | 76.2 (77/101) | < 0.001 | 91.9 (91/99) | 0.002 | 0.849 | < 0.001 |
Data are expressed as percentage (numbers). *Assessment category of masses based on B-mode US according to BI-RADS, †Comparison of diagnostic performance of between BI-RADS alone and addition of quantitative parameters.