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. 2020 Jun 24;21(9):1036–1044. doi: 10.3348/kjr.2019.0568

Table 3. Comparative Results of Qualitative and Quantitative Analyses between cDWI800, sDWI1000, sDWI1500, and cDWI1500.

Parameters cDWI800 sDWI1000 sDWI1500 cDWI1500 P P* P P P§
Suppression of normal glandular tissue 2.34 ± 0.79 2.66 ± 0.78 3.32 ± 0.90 3.66 ± 0.78 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
Overall image quality 3.31 ± 0.88 3.33 ± 0.84 3.35 ± 0.81 3.73 ± 0.62 < 0.001 > 0.999 0.002 > 0.999 0.002
Lesion conspicuity 2.83 ± 0.96 3.09 ± 0.94 3.52 ± 0.92 3.39 ± 0.90 < 0.001 < 0.001 < 0.001 < 0.001 0.051
CDR (invasive and in situ cancer), % 84.0 (42/50) 86.0 (43/50) 90.0 (45/50) 90.0 (45/50) 0.061
CDR (invasive cancer), % 89.7 (35/39) 92.3 (36/39) 94.9 (37/39) 94.9 (37/39) 0.194
Cancer-to-parenchyma contrast ratio 0.47 ± 0.17 0.54 ± 0.16 0.63 ± 0.17 0.55 ± 0.18 < 0.001 < 0.001 0.009 0.004 0.961

Pooled data from two readers are mean ± standard deviation. P values were calculated using Friedman test for qualitative anlaysis, Cochran's Q Test for CDR, and one-way ANOVA for cancer-to-parenchyma contrast ratio. *p values indicate comparisons between cDWI800 and sDWI1500 in post-hoc analysis, p values indicate comparisons between cDWI800 and cDWI1500 in post-hoc analysis, p values indicate comparisons between sDWI1000 and sDWI1500 in post-hoc analysis, §p values indicate comparisons between sDWI1000 and cDWI1500 in post-hoc analysis. CDR = cancer detection rate, cDWI800 = conventional low b-value (800 s/mm2) diffusion-weighted imaging, cDWI1500 = conventional high b-value (1500 s/mm2) diffusion-weighted imaging, sDWI1000 = synthetic high b-value (1000 s/mm2) diffusion-weighted imaging, sDWI1500 = synthetic high b-value (1500 s/mm2) diffusion-weighted imaging