Table 4.

Comparison between allergens, symptoms, and severity of symptoms in patients from the 1990s and 2010s

Allergen	Proportion of symptoms (%)
	Nasal obstruction			Rhinorrhea			Sneezing			Itching of the nose/eye
	1990s	2010s	P	1990s	2010s	P	1990s	2010s	P	1990s	2010s	P
Dermatophagoides pteronyssinus	91.2	92.7	0.132	85.8	83.9	0.159	78.8	77.1	0.293	50.3	61.4	< 0.001
Dermatophagoides farinae	90.8	92.1	0.227	85.5	83.5	0.143	79.0	77.1	0.222	49.0	60.8	< 0.001
Cat fur	92.7	93.0	0.817	89.4	84.7	0.016	81.4	77.3	0.077	52.9	63.9	< 0.001
Dog dander	93.6	93.5	0.969	87.5	87.3	0.942	81.6	80.2	0.571	52.8	65.0	< 0.001
Tree pollen	86.1	92.4	0.006	85.6	85.2	0.882	84.7	77.6	0.030	49.0	65.7	< 0.001

Allergen	Proportion of moderate-to-severe symptoms (%)
	Nasal obstruction			Rhinorrhea			Sneezing			Itching of the nose/eye
	1990s	2010s	P	1990s	2010s	P	1990s	2010s	P	1990s	2010s	P
Dermatophagoides pteronyssinus	63.7	70.2	<0.001	35.0	30.2	0.006	34.7	35.7	0.605	32.8	43.0	< 0.001
Dermatophagoides farinae	63.7	69.2	0.002	34.4	30.3	0.018	35.1	34.8	0.847	32.2	42.1	< 0.001
Cat fur	67.3	69.9	0.338	38.2	33.6	0.095	39.0	38.8	0.944	35.3	45.8	< 0.001
Dog dander	72.0	71.8	0.932	36.4	36.5	0.978	36.2	39.0	0.368	37.0	47.8	0.002
Tree pollen	57.9	70.3	0.001	33.7	36.6	0.446	41.1	37.7	0.388	32.2	44.0	0.003

* Chi square test