Table 1.
Mean mucosal peak eosinophil, mast cell, and TH17 densities in the rectosigmoid and descending colons of youth with IBS patients (n = 37) and controls (n = 10).
| Location | Cell type | IBS patients | Controls | P value |
|---|---|---|---|---|
| Rectosigmoid | Eosinophils | 19.0 ± 11.4 | 10.1 ± 6.0 | 0.022 |
| Rectosigmoid | Mast cells | 19.8 ± 6.4 | 10.7 ± 6.3 | < 0.001 |
| Rectosigmoid | TH17 cells | 1.2 ± 0.5 | 0.5 ± 0.5 | 0.001 |
| Descending | Eosinophils | 26.8 ± 15.1 | 15.2 ± 4.0 | < 0.001 |
| Descending | Mast cells | 21.5 ± 8.0 | 8.7 ± 2.9 | < 0.001 |
| Descending | TH17 cells | 1.2 ± 0.6 | 0.4 ± 0.5 | 0.001 |