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Mean mucosal peak eosinophil and mast cell densities in the rectosigmoid and descending colons of youth with IBS patients reporting pain relief with defecation (n = 19) vs. those reporting no pain relief (n = 18).
| Location | Cell type | Pain relieved | Pain not relieved | P value |
|---|---|---|---|---|
| Rectosigmoid | Eosinophils | 16.4 ± 8.3 | 21.7 ± 13.6 | 0.159 |
| Rectosigmoid | Mast cells | 22.3 ± 6.2 | 17.1 ± 5.7 | 0.011 |
| Descending | Eosinophils | 24.1 ± 12.7 | 29.7 ± 17.2 | 0.265 |
| Descending | Mast cells | 22.1 ± 6.8 | 20.8 ± 9.3 | 0.636 |
