Table 5.
Comparison of digit span task in DMD cases with proximal and distal mutations with control group.
| Cognitive domain and neuropsychological battery | Neuropsychological battery variables | Proximal Mean (SD) |
Distal Mean (SD) |
Control Mean (SD) |
Proximal Mean rank |
Distal Mean rank |
Control Mean rank |
Chi square | p-value | Multiple comparision p value |
||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prox vs distal | Control vs Prox | Control vs distal | ||||||||||
|
DIGIT span testa Short term memory working memory |
DSF | 4.73 (1.19) | 4.94 (1.21) | 5.52 (1.21) | 53.68 | 62.09 | 79.85 | 8.342 | 0.015 | 0.499 | 0.046 | 0.015 |
| DSB | 2.64 (1.29) | 2.66 (1.84) | 3.59 (1.26) | 53.05 | 59.87 | 81.16 | 11.103 | 0.004 | 0.823 | 0.018 | 0.004 | |
| Attention fraction | 0.32 (0.25) | 0.40 (0.36) | 0.23 (0.18) | 82.32 | 80.71 | 65.12 | 5.158 | 0.076 | 0.992 | 0.167 | 0.040 | |
aDigit span test: DMD distal (n = 48), DMD Pro-(n = 14), control (n = 87).