TABLE 3.
SNP | Chr | Nearby genes | EAa | NEA | EAFb | LAS GWAS |
AD GWAS |
||||
Betac | SEc | P-valuec | Betad | SEd | P-valued | ||||||
rs7610618 | 3 | TM4SF4–TM4SF1 | T | C | 0.01 | 0.8459 | 0.1490 | 1.44E-8 | NA | NA | NA |
rs17612742 | 4 | EDNRA | C | T | 0.21 | 0.1740 | 0.0278 | 1.46E-11 | −0.0562 | 0.0234 | 0.01618 |
rs10820405 | 9 | LINC01492 | G | A | 0.82 | 0.1823 | 0.0341 | 4.51E-08 | −0.0086 | 0.0198 | 0.6644 |
rs12124533 | 1 | TSPAN2 | T | C | 0.24 | 0.1570 | 0.0262 | 1.22E-8 | 0.0321 | 0.0187 | 0.08658 |
rs2107595 | 7 | HDAC9–TWIST1 | A | G | 0.24 | 0.1906 | 0.0233 | 3.65E-15 | −0.0038 | 0.0211 | 0.8582 |
aEffect allele associated with LAS. bThe frequency of effect allele associated with LAS. cThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from the published article (Malik et al., 2018). dThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from AD GWAS dataset.