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. 2020 Jul 14;11:581. doi: 10.3389/fgene.2020.00581

TABLE 3.

Characteristics of five genetic variants in LAS and AD GWAS datasets.

SNP Chr Nearby genes EAa NEA EAFb LAS GWAS
AD GWAS
Betac SEc P-valuec Betad SEd P-valued
rs7610618 3 TM4SF4–TM4SF1 T C 0.01 0.8459 0.1490 1.44E-8 NA NA NA
rs17612742 4 EDNRA C T 0.21 0.1740 0.0278 1.46E-11 −0.0562 0.0234 0.01618
rs10820405 9 LINC01492 G A 0.82 0.1823 0.0341 4.51E-08 −0.0086 0.0198 0.6644
rs12124533 1 TSPAN2 T C 0.24 0.1570 0.0262 1.22E-8 0.0321 0.0187 0.08658
rs2107595 7 HDAC9–TWIST1 A G 0.24 0.1906 0.0233 3.65E-15 −0.0038 0.0211 0.8582

aEffect allele associated with LAS. bThe frequency of effect allele associated with LAS. cThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from the published article (Malik et al., 2018). dThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from AD GWAS dataset.