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. 2020 Jul 14;11:581. doi: 10.3389/fgene.2020.00581

TABLE 4.

Characteristics of four genetic variants in CES and AD GWAS datasets.

SNP Chr Nearby genes EAa NEA EAFb CES GWAS
AD GWAS
Betac SEc P-valuec Betad SEd P-valued
rs146390073 1 RGS7 T C 0.02 0.6678 0.1205 2.20E-08 NA NA NA
rs6891174 5 NKX2-5 A G 0.35 0.1044 0.0206 5.82E-09 −0.0021 0.017 0.9006
rs13143308 4 PITX2 T G 0.34 0.2776 0.0193 1.86E-47 −0.0128 0.0188 0.4972
rs12932445 16 ZFHX3 C T 0.21 0.1823 0.0213 6.86E-18 −0.0261 0.0216 0.2272

aEffect allele associated with CES. bThe frequency of effect allele associated with CES. cThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from the published article (Malik et al., 2018). dThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from AD GWAS dataset.