TABLE 4.
SNP | Chr | Nearby genes | EAa | NEA | EAFb | CES GWAS |
AD GWAS |
||||
Betac | SEc | P-valuec | Betad | SEd | P-valued | ||||||
rs146390073 | 1 | RGS7 | T | C | 0.02 | 0.6678 | 0.1205 | 2.20E-08 | NA | NA | NA |
rs6891174 | 5 | NKX2-5 | A | G | 0.35 | 0.1044 | 0.0206 | 5.82E-09 | −0.0021 | 0.017 | 0.9006 |
rs13143308 | 4 | PITX2 | T | G | 0.34 | 0.2776 | 0.0193 | 1.86E-47 | −0.0128 | 0.0188 | 0.4972 |
rs12932445 | 16 | ZFHX3 | C | T | 0.21 | 0.1823 | 0.0213 | 6.86E-18 | −0.0261 | 0.0216 | 0.2272 |
aEffect allele associated with CES. bThe frequency of effect allele associated with CES. cThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from the published article (Malik et al., 2018). dThe summary statistics for SNP, including Beta, standard error, and P-value, were obtained from AD GWAS dataset.