Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 16;15:5131–5146. doi: 10.2147/IJN.S257084

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Ou et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

GP inhibitor inhibits invasion and migration in MG63 and U2OS cells. (A) The invasion of MG63 and U2OS cells were measured for 24 h using a Matrigel-coated chamber with polycarbonate filters. (B) Statistical analysis of the invasion cell ratio is presented for each group. *p < 0.05. (C) The wounds of confluent MG63 cells were created with 100 μL yellow tips and incubated with a lipo-inhibitor or GP-inhibitor (5 μg/mL). Images of the wound at different time points are shown, and the borders of the wound are shown by a pair of black lines. (D) Statistical analysis of cell migration by calculating the ratio of the final cell-free gap to the initial wound area. *p < 0.05. (E) The expression levels of twist1, N-cadherin and E-cadherin after treatment with lipo-inhibitor or GP-inhibitor were evaluated by qRT-PCR. *p < 0.05.