Table 2.
Characteristics of T1D participants with DQB1*06:02 by autoantibody status
| DQB1*06:02+ (n = 50)* | Ab+ (n = 33) | Ab− (n = 16) | P value | |
|---|---|---|---|---|
| HbA1c at diagnosis, % [mmol/mol] (mean ± SD) | 10.8 ± 2.8 [95 ± 7] (n = 42) | 11.3 ± 2.9 [100 ± 8] (n = 28) | 10.0 ± 2.6 [86 ± 5] (n = 14) | 0.170 |
| DKA at diagnosis (%) | 0.090 | |||
| Yes | 36 (n = 18) | 45 (n = 15) | 19 (n = 3) | |
| No | 44 (n = 22) | 36 (n = 12) | 63 (n = 10) | |
| Unknown | 20 (n = 10) | 18 (n = 6) | 19 (n = 3) | |
| HLA-DQ status (%) | 0.006 | |||
| DQB1*03:02 | 30 (n = 15) | 42 (n = 14) | 0 (n = 0) | 0.002 |
| DQB1*02:01 | 22 (n = 11) | 24 (n = 8) | 19 (n = 3) | 1.00 |
| Other | 48 (n = 24) | 33 (n = 11) | 81 (n = 13) | 0.002 |
*
Islet autoantibodies were measured in 49/50 0602+ individuals with T1D.