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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Oral Oncol. 2019 Sep 18;98:53–61. doi: 10.1016/j.oraloncology.2019.09.004

Figure 2. Haloplex targeted sequencing of frequently mutated genes in HNSCC.

Figure 2

Schematic overview of the gene mutations per cell line, obtained with targeted Haloplex sequencing. A red box represents a missense mutation, green a nonsense mutation, yellow a frameshift deletion, blue a frameshift insertion, purple a splice site mutation, grey an exomic deletion, orange both a missense mutation and a frameshift deletion, blue both a missense mutations and a splice site mutation. For CDKN2A encoding the p16 protein, the number between brackets indicates a single (1) or homozygous (2) loss of the locus. The mutation annotations per cell line and gene can be found in table S3.