Table 7.
Mean concentration (μg/mL) of antimicrobial residues in milk following intramammary administration
| Antimicrobial, quantity/dose | Number of days after last antimicrobials administration (two administrations (−1 and −2) at 24 h apart) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| −2 | −1 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | |
| Neomycin sulfate, 300 mg/6 g | 139.7 | 23.1 | 163.4 | 22.8 | 8.36 | 1.51 | 0.31 | < 0.15 | – | – | – | – | – | – |
| Neomycin sulfate, 200 mg/6 g | 63.4 | 6.13 | 53.1 | 8.30 | 0.62 | 0.15 | < 0.15 | – | – | – | – | – | – | – |
| Dihydrostreptomycin sulfate, 350 mg/10 mL | 241.0 | 137.0 | 268.0 | 13.6 | 4.4 | 1.34 | 0.655 | 0.48 | 0.38 | 0.36 | 0.28 | 0.24 | 0.15 | < 0.15 |
| Dihydrostreptomycin sulfate, 100 mg/4 g | 58.1 | 29.3 | 51.8 | 5.8 | 1.05 | 0.37 | 0.16 | < 0.15 | < 0.15 | < 0.15 | – | – | – | – |
| Kanamycin sulfate, 50 mg/10 mL | 10.2 | 9.6 | 15.3 | 3.03 | 0.68 | 0.18 | < 0.15 | – | – | – | – | – | – | – |
| Gentamicin sulfate, 50 mg/9 g | 6.46 | 3.72 | 5.74 | 1.29 | 0.66 | 0.25 | 0.16 | 0.083 | 0.065 | 0.035 | < 0.025 | < 0.025 | – | – |
| Procaine penicillin G, 450,000 IU/6 g | 48.5 | 2.65 | 86.08 | 5.16 | 0.548 | 0.08 | 0.011 | 0.002 | 0.001 | < 0.001 | – | – | – | – |
| Procaine penicillin G, 1,000,000 IU/10 mL | 291.0 | 182.3 | 289 | 9.26 | 0.551 | 0.044 | 0.008 | 0.002 | < 001 | – | – | – | – | – |
| Sodium cloxacillin, 200 mg/9 g | 35.9 | 6.86 | 37.5 | 1.68 | 0.2 | 0.02 | 0.01 | < 0.01 | – | – | – | – | – | – |
| Cefalexin monohydrate, 100 mg/10 mL | 3.1 | 2.94 | 3.21 | 0.051 | 0.031 | 0.02 | < 0.02 | < 0.02 | < 0.02 | – | – | – | – | – |