Table 5.
Summary of results.
| Summary Results | ||||
|---|---|---|---|---|
| Compound | 1 | 2 | 3 | Capsaicin |
| ED50 of maximal effect | 37.7 µM | 6.8 µM | 139.3 µM | 86.9 µM |
| Maximal percentage of analgesia attained | 83%At 3 h | 100%at 3 h | 75%at 7 h | 86%At 4 h |
| Concentration at maximal analgesia | 53 µM | 53 µM | 92 µM | 44 µM |
| Time to first effect | Hour 1 | Hour 1 | Hour 7 | Hour 3 |
| Effect duration (h) | 8 | 3 | 2 | 2 |
Estimated ED50 at maximal effect (row1), maximal analgesia attained (row 2), concentration at maximal analgesia (row 3), time to first significant effect (row 4) and effect duration (row 5) are shown for compound 1 (column 2), compound 2 (column 3), compound 3 (column 4) and capsaicin (column 5).