Table 2.

The association between 6 independent genetic variants and liver cT1. A linear mixed model was used for genetic associations (levels of significance: p <5×10⁻⁸).

SNP	CHR	Base pairs	EA	OA	EAF	Gene	Variant type	Amino acid change	BETA	Standard error	p value	Variance explained
rs759359281	1	220,100,497	C	CA	0.06	SLC30A10	Intron		0.137	0.026	2.8×10-8	0.23
rs13107325	4	103,188,709	T	C	0.07	SLC39A8	Missense	A391T	0.544	0.022	1.2×10-133	3.95
rs111723834	14	24,572,932	A	G	0.02	PCK2, NRL	Missense	A561G	0.291	0.046	3.0×10-11	0.27
rs58542926	19	19,379,549	T	C	0.07	TM6SF2	Missense, Intron	I148M	0.124	0.022	1.4×10-8	0.22
rs4820268	22	37,469,591	G	A	0.46	TMPRSS6	Missense	V736A	0.066	0.012	1.6×10-9	0.2
rs738409	22	44,324,727	G	C	0.21	PNPLA3	Missense	E167K	0.095	0.014	9.6×10-13	0.9

Effects are in SD.

CHR, chromosome; EA, effect allele; EAF, effect allele frequency; OA, other allele.