Table 1.
Clinical characteristics of the examined patients with COPD, asthma-COPD overlap, and bronchial asthma.
COPD | ACO | Bronchial asthma | p | |
---|---|---|---|---|
1 | 2 | 3 | ||
Subjects (n/%) | 58 | 57 | 32 | |
Men | 50 (86,3%) | 23 (40%) | 5 (15,6%) | p = 0.001 |
Women | 8 (13,7%) | 34 (60%) | 27 (84,4%) |
p
1−2 = 0.001 p1−3 = 0.001 p2−3 > 0.05 |
Age (years) | 63, 1 ± 9, 6 | 61, 78 ± 8, 55 | 58, 0 ± 7, 9 | p > 0.05 |
Smokers (abs./%) | 51/87,8 | 18/32,6 | 1/3,1 | p = 0.001 |
Smoking pack-years | 36, 0 ± 17, 9 | 36 ± 17, 9 | 9 |
p
1−2 > 05 p1−3 = 0.001 p2−3 = 0.001 |
FEV1 (after bronchodilator) (l) | 1, 6 ± 0, 7 | 1, 5 ± 0, 5 | 1, 8 ± 0, 54 | p > 0.05 |
FEV1 (after bronchodilator) (% pred) | 55, 3 ± 21, 2 | 60, 8 ± 0, 5 | 75, 15 ± 18, 76 |
p
1−2 = 0.033 p1−3 = 0.001 p2−3 = 0.001 |
FVC (l) | 3, 11 ± 0, 76 | 2, 77 ± 0, 76 | 2, 59 ± 0, 78 |
p
1−2 = 0.02 p1−3 = 0.003 p2−3 > 0.05 |
FVC (% pred) | 81, 05 ± 15, 05 | 88, 59 ± 19, 9 | 88, 77 ± 13, 7 |
p
1−2 = 0.02 p1−3 = 0.001 p2−3 > 0.05 |
FEV1/FVC (%) | 50, 5 ± 13, 0 | 53, 31 ± 10, 43 | 75, 56 ± 5, 1 |
p
1−2 > 0.05 p1−3 = 0.001 p2−3 = 0.001 |
IC (%) | 79, 23 ± 21, 64 | 90, 98 ± 23, 17 | 96, 14 ± 30, 76 |
p
1−2 = 0.01 p1−3 = 0.001 p2−3 > 0.05 |
Data were presented as mean ± SD. COPD: chronic obstructive pulmonary disease; ACO: asthma-COPD overlap; pack-years: number of cigarette packs per day multiplied by the number of smoking years; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity, IC: inspiratory capacity (%).