Table 5.
Correlation between the serum concentration TNF-α and the lung function parameters in patients with COPD, asthma-COPD overlap, and bronchial asthma.
| Spirometric indicators | COPD | ACO | BA | |||
|---|---|---|---|---|---|---|
| r | p | r | p | r | p | |
| FVC (l) | -0.32 | 0.03 | -0.36 | 0.051 | -0.25 | 0.35 |
| FVC (%) | -0.52 | 0.001 | -0.126 | 0.51 | -0.19 | 0.53 |
| FEV1 (l) | -0.318 | 0.04 | 0.006 | 0.97 | -0.47 | 0.03 |
| FEV1 (%) | -0.364 | 0.018 | 0.192 | 0.18 | -0.43 | 0.04 |
| FEV1/FVC (%) | -0.34 | 0.02 | -0.405 | 0.02 | -0.21 | 0.36 |
| FEF25 (l) | -0.279 | 0.074 | 0.266 | 0.15 | -0.27 | 0.33 |
| FEF25 (%) | -0.313 | 0.044 | 0.195 | 0.18 | -0.1 | 0.73 |
| FEF50 (l) | -0.274 | 0.079 | 0.223 | 0.23 | -0.26 | 0.34 |
| FEF50 (%) | -0.328 | 0.034 | -0.361 | 0.05 | 0.1 | 0.74 |
| FEF75 (l) | -0.24 | 0.12 | 0.087 | 0.64 | 0.25 | 0.35 |
| FEF75 (%) | -0.267 | 0.087 | 0.221 | 0.24 | -0.12 | 0.7 |
| IC (%) | -0.191 | 0.226 | 0.212 | 0.26 | -0.24 | 0.35 |
r: correlation coefficient; COPD: chronic obstructive pulmonary disease; ACO: asthma-COPD overlap; BA: bronchial asthma.