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. Author manuscript; available in PMC: 2020 Jul 21.
Published in final edited form as: Med Phys. 2019 Oct 31;46(12):5637–5651. doi: 10.1002/mp.13853

Table II.

Evaluation of the average segmentation results on ACDC dataset for RV blood-pool, LV myocardium, and LV blood-pool (mean value reported), obtained from all networks against the provided reference segmentation.

End diastole (ED)
End systole (ES)
SN DMR SN USN DMR USN UNet DMR UNet SN DMR SN USN DMR USN UNet DMR UNet

(a) Evaluation of Average (across all heart chambers) Segmentation Results
 Dice (%) 91.1 91.7** 91.5 92.0** 91.6 92.2** 87.3 88.0* 87.7 88.7** 87.2 88.8*
 Jaccard (%) 84.0 85.1** 84.7 85.5** 85.0 85.9** 78.1 79.3* 78.7 80.3** 78.3 80.4*
 MSD (mm) 0.55 0.53* 0.58 0.52* 0.54 0.53* 0.92 0.85 0.92 0.84 1.08 0.83
 HD (mm) 10.26 9.87 10.26 9.67 10.03 9.52 11.33 10.31* 11.66 10.91 12.61 10.96*

Correlation coefficient
Bias+LOA
SN DMR SN USN DMR USN UNet DMR UNet SN DMR SN USN DMR USN UNet DMR UNet

(b) Evaluation of the Clinical Indices
 LV EF 0.939 0.947 0.944 0.970 0.962 0.963 1.00 (13.15) 0.31 (12.44) 0.58 (12.57) −0.42 (9.24) 0.31 (10.41) 0.40 (10.40)
 RV EF 0.874 0.871 0.866 0.895 0.856 0.870 1.04 (17.40) 1.77 (17.34) 0.85 (17.40) 0.38 (15.42) 0.09 (18.94) 0.29 (18.30)
 Myo Mass 0.948 0.970 0.958 0.973 0.933 0.978 3.10 (32.94) −0.43 (25.17) 0.35 (29.65) 0.21 (23.89) 2.85 (37.39) 0.80 (21.75)

The statistical significance of the results for DM regularized model compared against the baseline model are represented by * and ** for P-values < 0.05 and 0.005, respectively. Also shown are the clinical indices evaluated for each heart chamber. The best performing model for each metric has been highlighted in bold. SN: SegNet, USN: USegNet, UNet: UNet.

Best performing model for the ED and ES phases are shown in bold case.