Fig. 3.

Microneutralization of antisera from mice immunized with various SARS vaccine candidates with pseudotyped SARS-CoV, pseudotyped and live SARS-CoV-2 viruses. Immunized mice groups were denoted as G1-G5, whereas mock alum-immunized mice were denoted as C. (a) Neutralizing activity can be observed in all five immunized groups. (b) Cross-neutralizing activity to ppSARS-2 can be detected only in Group 1, with no cross-neutralization observed in the other four groups. (c) Reexamination of mice antisera with live SARS-CoV-2 showed that neutralizing activity was only observed in Group 1.