Table 2.
Groundwater
| Compound (name and/or code) | Mobility in soil | > 0.1 μg/L at 1 m depth for the representative usesa | Pesticidal activity | Toxicological relevance |
|---|---|---|---|---|
| prosulfuron | Very high (KFoc = 4–37 mL/g) | Yes at 2 of 8 FOCUS scenarios Hamburg 0.125 μg/L Okehampton 0.127 μg/L | Yes | Yes |
| CGA159902 (prosulfuron phenyl sulfonamide) | High to very high (KFoc = 44–88 mL/g) | Yes at 7 of 8 FOCUS scenarios 0.139–0.373 μg/L only Sevilla < 0.1 μg/L | No | Open unlikely to be genotoxic, though is < 0.75 μg/L, as it is a plant metabolite, further information on combined food and water consumer intake is needed to conclude on non‐relevance |
| CGA150829 (triazine amine) | Medium to very high (KFoc = 3–225.5 mL/g) | Yes in at least 6 of 8 FOCUS scenarios 0.151–0.228 μg/L only Porto and Sevilla may be < 0.1 μg/L | No | Open in the absence of a conclusive assessment on the lack of genotoxicity and consumer risk assessmentb |
| CGA300406 (O‐desmethyl‐prosulfuron) | High to very high (KFoc = 42–126 mL/g) | No | No | Assessment not triggered unlikely to be genotoxic |
| CGA325025 (demethoxy amino‐prosulfuron) | Very high (KFoc = 21–32 mL/g) | Yes at 1 of 8 FOCUS scenarios Hamburg 0.124 μg/L | No | Yes in the absence of conclusive data on the lack of genotoxicity |
| CGA349707 | Very high (KFoc = 37–52 mL/g) | Yes at all 8 FOCUS scenarios 0.393–1.07 μg/L | No | No unlikely to be genotoxic an ADI of 0.001 mg/kg bw per day was set, consumer intake was up to 16.1% of this ADI |
| SYN542604 (M5) | Medium to very high (KFoc = 58–223 mL/g) | No | No | Assessment not triggered unlikely to be genotoxic |
| SYN547308 (M18) | Medium to high (KFoc = 65–288 mL/g) potential pH dependence | Yes at 5 of 8 FOCUS scenarios 0.14–0.223 μg/L Porto, Sevilla and Thiva < 0.1 μg/L | No | Open unlikely to be genotoxic, unclear if there might be residues in food, this would need to be clarified before non‐relevance could be concluded as a combined food and water consumer intake needs to be estimated |
| Unidentified (M17) | Data gap | Data gap | Open | Open |
a
At least one FOCUS scenario or relevant lysimeter.
b
It is acknowledged that the genotoxic potential of metabolite CGA150829 (triazine amine) has been assessed by the EFSA PPR Panel (EFSA PPR Panel, 2020). According to the EFSA PPR Panel, an in vitro Micronuclei test would be needed to conclude on its aneugenic potential. EFSA noted that considering the EFSA PPR Panel Opinion and given that aneugenicity is a threshold‐mechanism the setting of reference would be possible. However, further discussion is needed on the most appropriate basis for setting the reference values for triazine amine and finalise a consumer risk assessment and groundwater relevance assessment.