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. 2019 Sep 4;4:129. [Version 1] doi: 10.12688/wellcomeopenres.15408.1

Table 2. A summary of the recommended medical tests within the Vietnam Ministry of Health (MoH) hepatitis C virus (HCV) treatment guidelines.

Name of required tests Before treatment During treatment After treatment
Group 1: Electrocardiogram Electrocardiogram Yes No No
Group 2: Ultrasound Abdominal ultrasound Every 12 weeks
Fibro-scan No
Group 3: X-ray Chest X-ray No
Group 4: Blood tests Full blood count Every 4 weeks
The international normalized ratio No
Prothrombin Every 12 weeks
Group 5:Immunoassay Alpha-fetoprotein
Free thyroxine
Thyroid - Stimulating Hormone
Hepatitis B surface antigen No
Human immunodeficiency virus
Group 6: Biochemical tests Electrolytes
Albumin
Bilirubin
Creatinine (urine and blood) Every 4 weeks
Urea No
Alanine transaminase Every 4 weeks
Aspartate aminotransferase No
Gamma-glutamyl transferase No
Group 7: Molecular biology tests HCV-RNA viral load test Every 8 weeks Yes
HCV genotype real-time PCR No No

Before treatment, certain tests are required to assess disease severity and to ensure that treatment can be safely tolerated. During treatment, monitoring tests are required every 4, 8 or 12 weeks to assess treatment response and drug side effects. After treatment, the HCV-RNA viral load test is repeated to assess treatment response. This is based on the 2013 HCV treatment guidelines from the MoH 22.