Table 2. A summary of the recommended medical tests within the Vietnam Ministry of Health (MoH) hepatitis C virus (HCV) treatment guidelines.
Name of required tests | Before treatment | During treatment | After treatment | |
---|---|---|---|---|
Group 1: Electrocardiogram | Electrocardiogram | Yes | No | No |
Group 2: Ultrasound | Abdominal ultrasound | Every 12 weeks | ||
Fibro-scan | No | |||
Group 3: X-ray | Chest X-ray | No | ||
Group 4: Blood tests | Full blood count | Every 4 weeks | ||
The international normalized ratio | No | |||
Prothrombin | Every 12 weeks | |||
Group 5:Immunoassay | Alpha-fetoprotein | |||
Free thyroxine | ||||
Thyroid - Stimulating Hormone | ||||
Hepatitis B surface antigen | No | |||
Human immunodeficiency virus | ||||
Group 6: Biochemical tests | Electrolytes | |||
Albumin | ||||
Bilirubin | ||||
Creatinine (urine and blood) | Every 4 weeks | |||
Urea | No | |||
Alanine transaminase | Every 4 weeks | |||
Aspartate aminotransferase | No | |||
Gamma-glutamyl transferase | No | |||
Group 7: Molecular biology tests | HCV-RNA viral load test | Every 8 weeks | Yes | |
HCV genotype real-time PCR | No | No |
Before treatment, certain tests are required to assess disease severity and to ensure that treatment can be safely tolerated. During treatment, monitoring tests are required every 4, 8 or 12 weeks to assess treatment response and drug side effects. After treatment, the HCV-RNA viral load test is repeated to assess treatment response. This is based on the 2013 HCV treatment guidelines from the MoH 22.