Table 4.
Variables | Normal range | Total | Non-severe | Severe | p value |
---|---|---|---|---|---|
CD3+ lymphocytes, ×106/l | 690–2540 | 1279.10 (504.71) | 1342.67 (493.06) | 938.79 (429.62) | <0.0001**** |
CD4+CD3+ lymphocytes, ×106/l | 410–1590 | 767.93 (329.01) | 810.72 (321.02) | 530.61 (269.47) | <0.0001**** |
CD8+CD3+ lymphocytes, ×106/l | 190–1140 | 441.36 (200.65) | 455.71 (198.07) | 357.58 (198.21) | 0.0086** |
CD4+/CD8+ | 0.9–3.6 | 2.00 (1.01) | 2.02 (0.96) | 1.87 (1.27) | 0.0464* |
NLR | <1.2 | 2.16 (1.84) | 1.99 (1.04) | 3.28 (4.17) | 0.0010** |
Neutrophil count, ×106/l | 1.8–6.3 | 3.39 (1.39) | 3.35 (1.25) | 3.68 (2.09) | 0.8482 |
TLC, ×109/l | 1.1–3.2 | 1.78 (0.59) | 1.84 (0.59) | 1.44 (0.48) | <0.0001**** |
LDH, IU/l | 109–245 | 212.90 (58.50) | 205.84 (49.31) | 260.03 (87.35) | <0.0001**** |
CRP, mg/l | 0–10 | 1.82 (5.82) | 1.33 (2.57) | 5.02 (14.27) | 0.1671 |
Data was presented as mean (SD).
p < 0.05, **p < 0.01, ****p < 0.0001.
C3, complement 3; C4, complement 4; CD4+/CD8+, the ratio of CD4+ lymphocyte counts to CD8+ lymphocyte counts; COVID-19, coronavirus disease 2019; CRP, C-reactive protein; Ig, immunoglobulin; LDH, lactate dehydrogenase; NLR, neutrophil to lymphocyte ratio; TLC, total lymphocyte count.