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. Author manuscript; available in PMC: 2020 Jul 21.
Published in final edited form as: Drug Metabol Drug Interact. 2011 Nov 18;26(4):169–179. doi: 10.1515/DMDI.2011.027

Figure 2. Selected non-synonymous SNPs in ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8.

Figure 2

(A) The SNP A893S/T (black square) depicted in a topological diagram of ABCB1. (B) SNPs C43S (TM1), R433S and G671V (NBD1) (black squares) located in ABCC1. (C) SNP's V12M, Q141K (NBD) and D620N (extracellular loop) (black squares) in ABCG2. (D) Topological diagram of ABCG5 depicting the SNP Q604E (black square) implicated in sitosterolemia. (E) The SNPs D19H, Y54C, T400K and V632A (black squares) in a topological diagram of ABCG8.