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. 2020 Jul 21;11:84. doi: 10.1186/s40104-020-00482-x

Table 1.

Top five gene ontology terms in the four tissues

Tissue GO terms FDR
Muscle Biological Process
 Cellular respiration 1.51E-11
 Oxidation-reduction process 4.18E-11
 ATP synthesis coupled electron transport 8.73E-10
 Nucleobase-containing small molecule metabolic process 5.99E-09
 ATP metabolic process 5.28E-08
Cellular Component
 Mitochondrion 8.58E-14
 Mitochondrial respiratory 6.93E-13
 Respiratory chain complex 6.93E-13
 An inner mitochondrial membrane protein complex 4.88E-12
 Mitochondrial part 1.80E-11
Molecular Function
 Oxidoreductase activity 2.07E-12
 NADH dehydrogenase (ubiquinone) activity 6.48E-09
 Catalytic activity 6.57E-09
 Electron transfer activity 0.00029
 Cytochrome-c oxidase activity 0.0025
Liver Biological Process
 Oxidation-reduction process 3.08E-17
 Small-molecule metabolic process 1.32E-13
 Metabolic process 9.41E-11
 Cellular metabolic process 9.41E-11
 Cellular process 1.04E-08
Cellular Component
 Mitochondrion 8.72E-21
 Mitochondrial part 6.00E-19
 Cytoplasmic part 1.95E-13
 Cytoplasm 4.00E-13
 Mitochondrial membrane 1.82E-11
Molecular Function
 Oxidoreductase activity 4.54E-16
 Catalytic activity 1.61E-12
 Cofactor binding 2.96E-06
 Aldehyde dehydrogenase (NAD) activity 2.75E-05
 Coenzyme binding 5.48E-05
Spleen Biological Process
 Oxidation-reduction process 0.0117
Cellular Component
 Mitochondrial part 7.57E-10
 Mitochondrial membrane 6.12E-09
 Mitochondrial inner membrane 4.01E-08
 Mitochondrial membrane part 6.04E-08
 Inner mitochondrial membrane protein complex 0.00012
Molecular Function
 Oxidoreductase activity 0.0014
 NADH dehydrogenase (ubiquinone) activity 0.003
 Catalytic activity 0.014
Rumen Biological Process
 Positive regulation of mitochondrion organization 0.0356
 Cellular metabolic process 0.0356
 Organonitrogen compound metabolic process 0.0356
 Cellular modified amino acid metabolic process 0.0419
 Phosphorylation 0.0419
Cellular Component
 Mitochondrial part 0.00044
 Mitochondrial envelope 0.0016
 Cytoplasm 0.0028
 Mitochondrial membrane 0.0098
 Cytoplasmic part 0.0126
Molecular Function
 Drug binding 0.00042
 Kinase activity 0.0046
 Catalytic activity 0.0076
 Transferase activity 0.0076
 Carbohydrate derivative binding 0.0076