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. 2020 Jul 20;13:81. doi: 10.1186/s13048-020-00685-w

Fig. 3.

Fig. 3

Overexpression of circRNA-UBAP2 (OE-UBAP2) promoted proliferation and inhibited apoptosis of ovarian cancer cells. a, Relative expression of circRNA-UBAP2 in OVCAR-3 and ES-2 were upregulated after overexpressed UBAP2 measured by RT-qPCR assay. *P < 0.05 vs NC group. b, Proliferation of OVCAR-3 and ES-2 cells were remarkably promoted after overexpressed UBAP2 measured by CCK-8 assay. *P < 0.05 vs NC group. c, Apoptosis of OVCAR-3 and ES-2 cells were inhibited after overexpressed UBAP2 measured by flow cytometry. *P < 0.05, **P < 0.01 vs NC group. d, Cell cycle of OVCAR-3 and ES-2 cells were affected after overexpressed UBAP2 measured by flow cytometry. *P < 0.05 vs NC group. e, The expression of Apoptosis-related proteins Bcl-2, Bax and caspase-1 of OVCAR-3 and ES-2 cells were decreased after overexpressed UBAP2 measured by western blotting. *P < 0.05 vs NC group