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. 2020 Jul 20;13:81. doi: 10.1186/s13048-020-00685-w

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — circRNA-UBAP2 targeted miR-382-5p. a, The binding site of miR-382-5p and circRNA-UBAP2 was predicted by starBase. b, The interaction of circRNA-UBAP2 and miR-382-5p was determined by dual-luciferase reporter gene system. ^*P < 0.05 vs NC group. c, Knockdown and overexpression of circRNA-UBAP2 effected on the expression of miR-382-5p in SKOV3 and A2780 cells measured by RT-qPCR assay. ^*P < 0.05 vs NC group. d, Expression of miR-382-5p in ovarian cancer tissues and adjacent tissues were measured by RT-qPCR assay. ^**P < 0.01 vs adjacent tissues. e, The expression level of circRNA-UBAP2 was negatively related to miR-382-5p in ovarian cancer tissues measured by RT-qPCR assay. P < 0.0001