Table 3.

Spearman correlation coefficients between CSF NRG1 and other characteristics in AD patients

	Spearman correlation coefficients (p value)
	CSF neuregulin	Age	MMSE	CSF Aβ1–42	CSF Aβ1–40	CSF tau	CSF P-tau	CSF BACE1
CSF neuregulin	1
Age	− 0.14 (0.33)	1
MMSE	− 0.44 (0.001)	0.17 (0.24)	1
CSF Aβ1–42	0.28 (0.03)	0.01 (0.92)	− 0.24 (0.09)	1
CSF Aβ1–40	− 0.07 (0.61)	0.13 (0.37)	0.15 (0.32)	0.34 (0.01)	1
CSF tau	0.06 (0.66)	− 0.10 (0.47)	− 0.11 (0.45)	0.0 (0.98)	0.29 (0.04)	1
CSF P-tau	− 0.03 (0.81)	− 0.04 (0.78)	− 0.03 (0.83)	0.1 (0.85)	0.32 (0.02)	0.85 (< 0.001)	1
CSF BACE1	− 0.14 (0.32)	0.08 (0.55)	0.17 (0.23)	0.05 (0.72)	0.67 (< 0.001)	0.41 (0.002)	0.39 (0.004)	1

Correlations between CSF NRG1 levels and other characteristics in AD patients

Spearman correlation coefficient was used for statistical analysis