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. Author manuscript; available in PMC: 2020 Jul 21.
Published in final edited form as: Cell Rep. 2020 Jun 30;31(13):107840. doi: 10.1016/j.celrep.2020.107840

Figure 3. A Specific GRP94 Conformation Enables the Formation of Stable HMW GRP94 and HER2 Pools.

Figure 3.

(A) Anti-GRP94 antibody captured cargo from SKBr3 cell extracts, and the remaining supernatant was separated under native and denaturing conditions and immunoblotted with the indicated antibodies.+, 1 times antibody amount; ++, 2 times antibody amount. IgG, control; red arrow, unspecific signal.

(B) Immuno-capture as in (A) of SKBr3 cells treated with PU-WS13 in a dose and time-dependent manner. Graph, mean of 3 independent experiments; error bars, SEM.

(C) Summary of the findings.