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. 2020 Jul 14;13:113. doi: 10.3389/fnmol.2020.00113

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Copyright © 2020 Shah, Mittal, Shahal, Sinha, Bulut, Mittal and Eshraghi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TDCA attenuates EIT induced oxidative stress in OC explants. (A) CellROX immunostaining in OC explants subjected to EIT or EIT and treated with TDCA. The first column shows the explant’s stereocilia bundles stained with FITC-phalloidin. Cell nuclei were stained with DAPI (blue color). (B) The mean signal intensity for CellROX was calculated using ImageJ software. Data are expressed as mean values ± SD and are representative of three independent experiments. *P < 0.001 compared to the EIT group. n = 6 OCs per group. Scale bars: 10 μm.