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. 2020 Jul 21;32(3):107920. doi: 10.1016/j.celrep.2020.107920

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© 2020 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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RABV Neutralizing Titers over Time

Development of RABV neutralizing antibodies over time, averaged from mice in groups of mice (n = 10 mice per group, analyzed in duplicate, mean ± SD) immunized on days 0, 7, and 28 with either rRABV (blue), rMOKV (red), or LyssaVax (purple), or mock immunized (gray). See Figure 3A for full immunization scheme. Titers were calculated in international units (IU) per milliliter by comparison with the US standard rabies immune globulin. Level of detection (LOD) was 4 IU/mL. Two-way ANOVA and Tukey’s multiple comparisons tests were performed. ^∗p = 0.034, comparing rRABV and LyssaVax. See also Table S1 and Figure S6.