Figure 5.

MOKV G Pseudotype Neutralizing Titers

VNA titers against MOKV G pseudotype viruses (PTVs). PTVs made by trans-complementing VSVΔG-NanoLuc-EGFP with MOKV G (Figure S7). VNA titers measured in sera from mice immunized with either LyssaVax (purple open circle), rRABV (blue open square), or rMOKV (red open triangle), or mock immunized with PBS (gray open inverted triangle).

(A–C) Average titers shown over time: day 7 (A), day 14 (B), and day 35 (C) (n = 10 mice per group, analyzed in triplicate, mean ± SD).

(D) Pseudotype neutralization by the mAb 1409-7. Luminescence data background subtracted using paired sera from day 0 and normalized to 100% infection in no-sera controls.

(E) Serum IC₅₀ data analyzed by the Mann-Whitney test (^∗p = 0.0133).