Table 2.

Effect of various pharmacological treatments on oxidative stress parameters in rats

Parameter	Group
	Vehicle control	Cisplatin control (5 mg/kg, i.p.)	Cisplatin + sinapic (20 mg/kg, p.o.)	Cisplatin + sinapic 40 mg	Cisplatin + sinapic 40mg + BADGE
TBARS (µM/mg of protein)	0.45 ± 0.04	1.55 ± 0.05a	0.75 ± 0.04b	0.58 ± 0.03b	1.28 ± 0.07c
SAG (µM/mg of tissue)	21.4 ± 0.64	65.2 ±1.39a	45.1 ± 1.24b	35.2 ± 0.86b	62.8 ± 1.38c
MPO (U/g of tissue)	1.79 ± 0.52	6.91 ± 0.91a	5.02 ± 2.31b	2.06 ± 0.63b	5.24 ± 0.96c
GSH (mM/mg of protein)	16.2 ± 0.41	5.35 ± 0.52a	12.65 ± 0.52b	14.18 ± 0.33b	7.82 ± 0.64c

TBARS = thiobarbituric acid reactive substances, SAG = superoxide anion generation, MPO = myeloperoxidase, GSH = glutathione, BADGE = bisphenol A diglycidyl ether, i.p. = intraperitoneal, p.o. = orally

Data were expressed as mean ± standard error of mean (n = 6)

^aP < 0.05 versus vehicle control group

^bP < 0.05 versus cisplatin (5 mg/kg, i.p.)

^cP < 0.05 versus cisplatin + sinapic acid (40 mg/kg, p.o.)