Table 3.
Multivariable Linear Regression Examining Leukocyte Telomere Length at Year 25 (2010/2011) Among African Americans in the Coronary Artery Risk Development in Young Adults (CARDIA) Telomere Ancillary Study
Model 1: LTL, Year 15 |
Model 2: LTL, Year 25 |
Model 3: LTL, Year 25 |
Model 4: LTL, Year 25 |
|||||
---|---|---|---|---|---|---|---|---|
Variable | b | 95% CI | b | 95% CI | b | 95% CI | b | 95% CI |
Racial discrimination, Y15 | .006 | [−.017, .034] | .017 | [−.001, .035] | .015 | [>.000, .029] | ||
Racial discrimination, Y25 | −.009 | [−.024, .005] | −.019 | [−.038, −.001]* | −.019 | [−.035, −.004]* | ||
Telomere length, Y15 | .326 | [.280, .373]*** | ||||||
Age | −.003 | [−.010, .005] | −.002 | [−.009, .005] | −.002 | [−.009, .005] | .001 | [−.004, .007] |
Years elapsed Y15 to Y25 | .005 | [−.077, .087] | .001 | [−.082, .084] | −.001 | [−.084, .082] | −.021 | [−.091, .048] |
Women vs. Men | .047 | [−.018, .112] | .044 | [−.021, .109] | .048 | [−.016, .112] | .042 | [−.010, .095] |
> High school vs. ≤ high school | .008 | [−.052, .068] | .018 | [−.043, .078] | .011 | [−.049, .071] | −.028 | [−.079, .022] |
Household income | −.006 | [−.023, .011] | −.004 | [−.021, .013] | −.005 | [−.022, .012] | −.003 | [−.018, .012] |
Not working vs. working | −.031 | [−.102, .039] | −.030 | [−.101, .040] | −.024 | [−.094, .047] | −.007 | [−.068, .053] |
Relationship status (ref: Married) | ||||||||
Divorced, separated, widowed | −.016 | [−.086, .055] | −.011 | [−.081, .060] | −.012 | [−.083, .058] | −.021 | [−.084, .042] |
Never married | −.031 | [−.102, .041] | −.032 | [−.103, .039] | −.026 | [−.097, .045] | −.017 | [−.077, .043] |
Body Mass Indexa | −.003 | [−.007, .001] | −.003 | [−.007, .001] | −.003 | [−.007, .002] | −.002 | [−.006, .001] |
Former vs. never smoker | .060 | [−.023, .143] | .067 | [−.016, .151] | .061 | [−.023, .145] | .054 | [−.011, .120] |
Current vs. never smoker | −.034 | [−.098, .030] | −.032 | [−.096, .032] | −.034 | [−.098, .030] | −.008 | [−.065, .048] |
Note. N = 391. Age, education, household income, work status, marital status, smoking, and body mass index measured at Year 15. CI = confidence interval; Y15 = Year 15; Y25 = Year 25.
Body mass index calculated as (weight in kilograms)/(height in meters)2.
p < .05.
p < .001.