Table 1.
Characteristics of the study population
| Controls | EoE cases | ||
|---|---|---|---|
| (n = 20) | (n = 19) | P* | |
| Mean age (±SD) | 58.7 ± 12.5 | 34.9 ± 8.1 | <0.001 |
| Males (n, %) | 5 (25) | 9 (47) | 0.15 |
| White (n, %) | 16 (80) | 19 (100) | 0.04 |
| Symptoms | |||
| Dysphagia | 19 (95) | 19 (100) | 0.32 |
| Heartburn | 1 (5) | 0 (0) | 0.32 |
| Atopic conditions (n, %) | |||
| Asthma | 8 (40) | 8 (42) | 0.89 |
| Dermatitis | 1 (5) | 2 (11) | 0.58 |
| Seasonal allergies | 8 (40) | 12 (63) | 0.25 |
| Food allergies | 3 (15) | 4 (21) | 0.73 |
| Any atopic condition | 10 (50) | 14 (74) | 0.25 |
| Diagnoses | |||
| EoE | 0 (0) | 19 (100) | – |
| GERD | 6 (30) | 0 (0) | – |
| Esophageal dysmotility | 5 (25) | 0 (0) | – |
| Functional | 4 (20) | 0 (0) | – |
| Schatzki's ring | 3 (15) | 0 (0) | |
| Normal | 2 (10) | 0 (0) | |
| Tissue eosinophil counts (max eos/hpf ± SD) | 0 ± 0 | 157 ± 29.3 | <0.0001 |
| Peripheral blood absolute eosinophil counts (AEC) (mean cells/μL ± SEM) | 195 ± 38.03 | 363.2 ± 46.65 | 0.008 |
EoE, eosinophilic esophagitis; eos/hpf, eosinophils per high powered field; SD, standard deviation.