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. 2020 Jun 9;11(3):e01216-20. doi: 10.1128/mBio.01216-20

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FIG 4 — KL-2 reduces the recruitment of the SEC to viral IE promoters. (A and B) HFF cells were treated with vehicle or 8 μM KL-2 and infected with HSV (MOI = 2) for 2 h. (A) ChIP assay data showing the levels of the SEC (AFF4) associated with viral IE (ICP0 and ICP4), control viral (LAT), or control cellular (HSPA8) genes in cells treated with vehicle or KL-2. Data are means ± SEM of results from 4 experiments (paired two-tailed t tests). (B) Ratio of AFF4 occupancy levels in KL-2-treated versus vehicle-treated cells.