Table 2. Summary of neuronal ion channel gene expression in TAF1-depleted cells by qRT-PCR array analysis.
| Gene symbol | Gene description | Log 2 fold change |
|---|---|---|
| ASIC2 | ASIC2 plays a role in neurotransmission | 6.03 |
| ASIC3 | ASIC3 may play an important role in the detection of lasting pH changes | 3.88 |
| KCNJ14 | KCNJ14 probably has a role in controlling the excitability of motor neurones | 2.74 |
| CACNG4 | CACNG4 regulates both trafficking and channel gating of the AMPA receptors | 2.00 |
| KCNAB3 | KCNAB3 regulates the activity of the α subunit | 2.00 |
| CACNA1G | CACNA1G subunit mediates the entry of calcium ions into excitable cells; also involved in a variety of calcium-dependent processes | −2.00 |
| HCN2 | HCN2 involved in the generation of native pacemaker activity in the heart and in the brain | −2.00 |
| KCNH2 | KCNH2 is a voltage-activated potassium channel belonging to the eag family | −2.21 |
Abbreviation: AMPA, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor.